Fig. 1 · Structure
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4-Hydroxy atorvastatin hemicalcium
Atorvastati metabolite
4-Hydroxy atorvastatin hemicalcium is a metabolite of the widely studied HMG-CoA reductase inhibitor, atorvastatin. This compound exhibits significant lipid-lowering activity, contributing to the therapeutic efficacy of atorvastatin in managing hyperlipidemia. Research applications include studying the metabolic pathways of atorvastatin and evaluating its pharmacokinetic properties in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 265989-44-4 |
| Applications | Atorvastati metabolite |
| Formula | C33H35FN2O6.1/2Ca |
| Molecular Weight | 594.68 |
| SMILES | O[C@@H](C[C@@H](O)CC(O)=O)CCN1C(C(C=C2)=CC=C2F)=C(C3=CC=CC=C3)C(C(NC(C=C4)=CC=C4O)=O)=C1C(C)C.[Ca] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.