Fig. 1 · Structure
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4-hydroxy Nonenal Mercapturic Acid
Unsaturated Fatty Acid
4-Hydroxy Nonenal Mercapturic Acid (4-HNE) is a metabolic product formed from the peroxidation of ω-6 polyunsaturated fatty acids, including linoleic acid, dihomo-γ-linolenic acid, and arachidonic acid. This compound is primarily involved in the detoxification pathways, rapidly cleared from plasma, and excreted in the urine as mercapturic acid conjugates. Research applications encompass investigations into oxidative stress, lipid peroxidation, and the resulting effects on cellular signaling and disease mechanisms, particularly in relation to inflammation and metabolic disorders. The identification of its various metabolites enriches understanding of metabolic and detoxification processes in vivo.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 146764-24-1 |
| Applications | Unsaturated Fatty Acid |
| Formula | C14H25NO5S |
| Molecular Weight | 319.42 |
| SMILES | OC1CC(SCC(NC(C)=O)C(O)=O)C(CCCCC)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.