Fig. 1 · Structure
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4-Hydroxymephenytoin
Mephenytoin Metabolism
4-Hydroxymephenytoin is a metabolite of the antiepileptic drug mephenytoin, primarily involved in the evaluation of CYP2C19 enzyme activity. It serves as a valuable substrate for studying the pharmacokinetics and metabolism of therapeutic agents within the cytochrome P450 system. This compound is instrumental in research applications focusing on drug interactions, personalized medicine, and pharmacogenomics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 61837-65-8 |
| Applications | Mephenytoin Metabolism |
| Formula | C12H14N2O3 |
| Molecular Weight | 234.25 |
| SMILES | O=C1N(C)C(C(C2=CC=C(O)C=C2)(CC)N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.