Fig. 1 · Structure
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4-Hydroxyphenylbutazone
Metabolite of Phenylbutazone
4-Hydroxyphenylbutazone is a metabolite of the nonsteroidal anti-inflammatory drug Phenylbutazone, functioning as a reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Its key biological activity involves modulation of inflammatory processes, making it relevant for research on pain and inflammation pathways. This compound is useful in studies investigating the metabolism and pharmacokinetics of NSAIDs, as well as their effects on prostaglandin biosynthesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 16860-43-8 |
| Applications | Metabolite of Phenylbutazone |
| Formula | C19H20N2O3 |
| Molecular Weight | 324.37 |
| SMILES | O=C(C1(CCCC)O)N(C2=CC=CC=C2)N(C3=CC=CC=C3)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.