Fig. 1 · Structure
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4-Hydroxytolbutamide-d9
Stable Isotope
4-Hydroxytolbutamide-d9 is a deuterium-labeled derivative of 4-Hydroxytolbutamide, a metabolite of the oral antidiabetic agent Tolbutamide. This compound primarily targets cytochrome P450 enzymes CYP2C8 and CYP2C9, which are involved in its metabolism. It is utilized in pharmacokinetic studies and metabolic profiling to trace the metabolic pathways of sulfonylureas and to assess their efficacy in diabetes research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1185112-19-9 |
| Applications | Stable Isotope |
| Formula | C12H9D9N2O4S |
| Molecular Weight | 295.40 |
| Synonyms | Hydroxytolbutamide-d9 |
| SMILES | O=S(C1=CC=C(CO)C=C1)(NC(NC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.