Fig. 1 · Structure

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4-Maleimidobenzoic acid

Protein Crosslinker

4-Maleimidobenzoic acid functions as a protein crosslinker through its maleimide functional group, which specifically reacts with sulfhydryl groups on cysteine residues. This compound is often utilized in the development of maleimidobenzoyl spacers, facilitating the stabilization and modification of protein complexes. Its application is essential in protein engineering and bioconjugation studies, offering researchers a means to investigate protein interactions and dynamics.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 17057-04-4
Applications Protein Crosslinker
Formula C11H7NO4
Molecular Weight 217.18
SMILES
C1=C(C=CC(=C1)N2C(=O)C=CC2=O)C(=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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