4-Methoxycinnamyl alcohol targets histone methyltransferases and exhibits significant anticancer properties. It demonstrates cytotoxic activity against MCF-7, HeLa, and DU145 cancer cell lines, with IC50 values of 14.24, 7.82, and 22.10 μg/mL, respectively. Notably, 4-Methoxycinnamyl alcohol induces cell necrosis rather than apoptosis, as evidenced by a 48-hour DNA fragmentation assay. This compound is derived from Foeniculum vulgare, highlighting its potential relevance in cancer research applications.
4-Methoxycinnamyl alcohol targets histone methyltransferases and exhibits significant anticancer properties. It demonstrates cytotoxic activity against MCF-7, HeLa, and DU145 cancer cell lines, with IC50 values of 14.24, 7.82, and 22.10 μg/mL, respectively. Notably, 4-Methoxycinnamyl alcohol induces cell necrosis rather than apoptosis, as evidenced by a 48-hour DNA fragmentation assay. This compound is derived from Foeniculum vulgare, highlighting its potential relevance in cancer research applications.
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