Fig. 1 · Structure

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4-N-Maleimidobenzoicacid-NHS

Biochemical Assay Reagent

4-N-Maleimidobenzoicacid-NHS functions primarily as a bioconjugation reagent, targeting thiol groups for selective covalent attachment. The maleimide moiety enables efficient coupling of proteins, peptides, or other biomolecules to thiol-containing entities. In addition, the NHS ester readily reacts with primary amines, such as lysine side chains or aminosilane-coated surfaces, under neutral to slightly basic conditions, forming stable covalent bonds. This compound is ideal for use in biochemical assays, protein labeling, and other applications requiring precise functionalization.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 64191-06-6
Applications Biochemical Assay Reagent
Formula C15H10N2O6
Molecular Weight 314.25
SMILES
O=C(C1=CC=C(N2C(C=CC2=O)=O)C=C1)ON3C(CCC3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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