4-Oxofenretinide-d4

Catalog No.: A33125
Stable Isotope
4-Oxofenretinide-d4 is a deuterium-labeled derivative of 4-Oxofenretinide, specifically designed for use as a stable isotope in research applications. 4-Oxofenretinide is recognized for its ability to inhibit cell growth in various cancer cell lines, including ovarian, breast, and neuroblastoma. It facilitates the accumulation of cells in the G2-M phase of the cell cycle and triggers apoptosis in cancer cells via activation of caspase-9. This reagent is essential for studies focusing on cancer biology and therapeutic development.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description4-Oxofenretinide-d4 is a deuterium-labeled derivative of 4-Oxofenretinide, specifically designed for use as a stable isotope in research applications. 4-Oxofenretinide is recognized for its ability to inhibit cell growth in various cancer cell lines, including ovarian, breast, and neuroblastoma. It facilitates the accumulation of cells in the G2-M phase of the cell cycle and triggers apoptosis in cancer cells via activation of caspase-9. This reagent is essential for studies focusing on cancer biology and therapeutic development.
Product Information
Catalog NumA33125
FormulaC26H27D4NO3
Molecular Weight409.55
CAS Number2991099-34-2
SMILESCC(/C=C/C=C(/C=C/C1=C(C(CCC(C)1C)=O)C)C)=C\C(NC2=C([2H])C([2H])=C(O)C([2H])=C2[2H])=O
Synonyms4-Oxo-4-HPR-d4
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