4-(Trifluoromethyl)aniline-d4 is a deuterium-labeled derivative of 4-(Trifluoromethyl)aniline, known for its specificity as a dual inhibitor of DYRK1A and DYRK1B kinases, with IC50 values of 54.84 nM and 186.40 nM, respectively. This stable isotope is primarily used in metabolic studies and tracing experiments to elucidate biochemical pathways involving DYRK kinases. It serves as a valuable tool in chemical biology and pharmacological research focused on kinase inhibition and the development of therapeutic strategies.
4-(Trifluoromethyl)aniline-d4 is a deuterium-labeled derivative of 4-(Trifluoromethyl)aniline, known for its specificity as a dual inhibitor of DYRK1A and DYRK1B kinases, with IC50 values of 54.84 nM and 186.40 nM, respectively. This stable isotope is primarily used in metabolic studies and tracing experiments to elucidate biochemical pathways involving DYRK kinases. It serves as a valuable tool in chemical biology and pharmacological research focused on kinase inhibition and the development of therapeutic strategies.
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