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4010B-30

ApoA-I Upregulator

4010B-30 is an apolipoprotein A-I (ApoA-I) upregulator that primarily targets the peroxisome proliferator-activated receptor gamma (PPARγ). This compound enhances ApoA-I gene expression, leading to increased cholesterol efflux and the upregulation of ATP-binding cassette transporter A1 (ABCA1). Research indicates that 4010B-30 confers protective effects against the development of atherosclerotic lesions in ApoE-/- mice, making it a valuable tool for studying lipid metabolism and cardiovascular diseases.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1415477-76-7
Applications	ApoA-I Upregulator
Formula	C₁₇H₂₀F₄N₂O
Molecular Weight	344.35
SMILES	O=C(C1=CC=C(F)C(C(F)(F)F)=C1)N2CC3(CCN(C)CC3)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.