Fig. 1 · Structure
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4A3-Cit
ionizable lipid
4A3-Cit is an ionizable lipid that facilitates the formation of lipid nanoparticles (LNPs) for drug delivery applications. It provides an essential component in the design of LNPs, allowing for efficient encapsulation and release of therapeutic agents, particularly nucleotides. This lipid is widely utilized in the development of mRNA vaccines and gene therapy, due to its ability to enhance cellular uptake and improve bioavailability of delivered compounds.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2768211-13-6 |
| Applications | ionizable lipid |
| Formula | C83H147N3O16S4 |
| Molecular Weight | 1571.33 |
| SMILES | O=C(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)C)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)OCCOC(C(CSCCC(CC/C=C(C)\C)C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.