Fig. 1 · Structure
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4F 4PP oxalate
5-HT2A Antagonist
4F 4PP oxalate is a selective antagonist of the 5-HT2A receptor, demonstrating a high binding affinity with a Ki value of 5.3 nM. Its specificity is notable, exhibiting significantly lower affinity for the 5-HT2C receptor (Ki = 620 nM). This distinct profile makes 4F 4PP oxalate a valuable tool for research applications in neuropharmacology, particularly in the study of serotonin-related pathways and potential therapeutic interventions for psychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 144734-36-1 |
| Applications | 5-HT2A Antagonist |
| Formula | C24H28FNO5 |
| Molecular Weight | 429.48 |
| SMILES | O=C(C1=CC=C(F)C=C1)C2CCN(CCCCC3=CC=CC=C3)CC2.O=C(O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.