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4H-Tomentosin

sEH Inhibitor

4H-Tomentosin is a mixed-competitive inhibitor of soluble epoxide hydrolase (sEH), demonstrating an IC50 of 6.84 μM and a Ki value of 7.02 μM. This compound interacts with the sEH enzyme through hydrogen bonding with key residues such as Tyr343, Ile363, and Tyr383. Its ability to effectively inhibit sEH makes it a valuable tool for research into lipid signaling pathways and the modulation of inflammatory responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	68776-19-2
Applications	sEH Inhibitor
Formula	C₁₅H₂₂O₃
Molecular Weight	250.33
SMILES	O=C1OC2CC(C)C(CCC(C)O)=CCC2C1=C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.