(4S)-10-Nor-calamenen-10-one

Catalog No.: A65185
Sesquiterpene
(4S)-10-Nor-calamenen-10-one, a eudesmane sesquiterpene, primarily enhances lipopolysaccharide (LPS)-induced nitric oxide (NO) production in microglial cells. This compound, isolated from Alpinia oxyphylla, serves as a valuable tool for investigating neuroinflammatory responses and exploring the roles of microglia in various neurodegenerative diseases. Its ability to modulate inflammatory pathways makes it useful for biological research focused on neuroinflammation and related therapeutic strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(4S)-10-Nor-calamenen-10-one, a eudesmane sesquiterpene, primarily enhances lipopolysaccharide (LPS)-induced nitric oxide (NO) production in microglial cells. This compound, isolated from Alpinia oxyphylla, serves as a valuable tool for investigating neuroinflammatory responses and exploring the roles of microglia in various neurodegenerative diseases. Its ability to modulate inflammatory pathways makes it useful for biological research focused on neuroinflammation and related therapeutic strategies.
Product Information
Catalog NumA65185
FormulaC14H18O
Molecular Weight202.29
CAS Number1270089-06-9
SMILESCC([C@H]1C2=CC(C)=CC=C2C(CC1)=O)C
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