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5-Acetamide-Butenolide

Mycotoxin

5-Acetamide-Butenolide is a mycotoxin characterized by its pro-oxidant activity, primarily derived from the genus Fusarium. This compound disrupts mitochondrial membrane potential in primary neonatal rat cardiomyocytes and promotes the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. Additionally, 5-Acetamide-Butenolide increases reactive oxygen species (ROS) levels, decreases glutathione (GSH) concentrations, and diminishes the viability of HepG2 cells, making it valuable for research on oxidative stress and mitochondrial dysfunction.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	16275-44-8
Applications	Mycotoxin
Formula	C₆H₇NO₃
Molecular Weight	141.12
Synonyms	Butenolide
SMILES	O=C1OC(NC(C)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.