Fig. 1 · Structure

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5-Bromo-3-phenyl salicylic acid

AKR1C1 Inhibitor

5-Bromo-3-phenyl salicylic acid is a selective inhibitor of the enzyme AKR1C1, specifically targeting human 20α-hydroxysteroid dehydrogenase with an inhibition constant (Ki) of 140 nM. This compound demonstrates potent biological activity and is valuable for research in steroid metabolism and related signaling pathways. It may be applied in studies investigating the role of AKR1C1 in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 99514-99-5
Applications AKR1C1 Inhibitor
Formula C13H9BrO3
Molecular Weight 293.11
SMILES
O=C(C1=CC(Br)=CC(C2=CC=CC=C2)=C1O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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