Fig. 1 · Structure
Documents & Downloads
5-Bromomethylthalidomide
E3 Ligase Activator
5-Bromomethylthalidomide is an E3 ligase activator that facilitates protein ubiquitination, thereby influencing protein stability and degradation pathways. This compound serves as a key tool in research focused on targeted protein degradation and cellular regulation mechanisms. Its potential for further derivatization through bromide substitution enhances its utility in chemical biology and therapeutic research.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1312023-72-5 |
| Applications | E3 Ligase Activator |
| Formula | C14H11BrN2O4 |
| Molecular Weight | 351.15 |
| SMILES | O=C1C2=CC=C(CBr)C=C2C(N1C3C(NC(CC3)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.