5-Carboxamidotryptamine (5-CT) is a potent agonist of the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 serotonin receptors. With a Ki value of 4.6 nM for the human cloned 5-HT5A receptor, it exhibits significant biological activity. Research applications include studies on serotonin signaling pathways and investigations into temperature regulation in animal models, evidenced by its ability to induce a dose-dependent decrease in rectal temperature in mice.
5-Carboxamidotryptamine (5-CT) is a potent agonist of the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 serotonin receptors. With a Ki value of 4.6 nM for the human cloned 5-HT5A receptor, it exhibits significant biological activity. Research applications include studies on serotonin signaling pathways and investigations into temperature regulation in animal models, evidenced by its ability to induce a dose-dependent decrease in rectal temperature in mice.
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