Fig. 1 · Structure
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5-Carboxy-2′-deoxyuridine
Trifluridine Metabolite
5-Carboxy-2′-deoxyuridine is a metabolite derived from Trifluridine, functioning primarily through the modulation of nucleotide metabolism. This compound is a methyl oxidation product of Thymidine that can be generated via menadione-mediated photosensitization. It holds significance in chemical research for studying nucleoside alterations and their impact on cellular processes, making it valuable for investigations in cancer and antiviral therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14599-46-3 |
| Applications | Trifluridine Metabolite |
| Formula | C10H12N2O7 |
| Molecular Weight | 272.21 |
| SMILES | O[C@H]1C[C@H](N2C(NC(C(C(O)=O)=C2)=O)=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.