Fig. 1 · Structure
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5-Chloroisoquinoline
SARM1 Inhibitor
5-Chloroisoquinoline is a selective inhibitor of SARM1 (Sterile alpha and toll/interleukin receptor motif containing protein 1), which plays a critical role in axon degeneration by engaging in complex enzymatic activities. This compound serves as a valuable tool for research into neurodegenerative diseases and mechanisms of axon degeneration, facilitating investigations into potential therapeutic interventions. Its unique mechanism offers insights into the molecular pathways underlying neuronal health and degeneration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5430-45-5 |
| Applications | SARM1 Inhibitor |
| Formula | C9H6ClN |
| Molecular Weight | 163.60 |
| SMILES | ClC1=CC=CC2=CN=CC=C21 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.