Fig. 1 · Structure
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5'-Cholesteryl-TEG phosphoramidite
DNA/RNA Synthesi
5'-Cholesteryl-TEG phosphoramidite is a key reagent for the synthesis of oligonucleotides, targeting the incorporation of cholesterol and triethylene glycol moieties. This phosphoramidite enhances the stability and cellular uptake of nucleic acids, making it valuable for applications in antisense therapy, RNA interference, and DNA-based drug delivery systems. Its structural features facilitate the development of modified oligonucleotides, contributing to advancements in molecular biology and genetic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1325147-19-0 |
| Applications | DNA/RNA Synthesi |
| Formula | C46H82N3O7P |
| Molecular Weight | 820.13 |
| SMILES | C[C@@]12[C@]3([H])[C@](CC=C1C[C@@H](OC(NCCCOCCOCCOCCOP(OCCC#N)N(C(C)C)C(C)C)=O)CC2)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.