Fig. 1 · Structure

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5'-DMTr-dG(iBu)-Methyl phosphonamidite

For Oligonucleotide Synthesis

5'-DMTr-dG(iBu)-Methyl phosphonamidite is a phosphoramidite monomer designed for use in oligonucleotide synthesis. It serves as a critical building block for generating a variety of modified oligonucleotides, enabling the study of nucleic acid interactions and functions. This reagent is particularly valuable in research applications involving gene editing, antisense oligonucleotides, and RNA interference.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 115131-08-3
Applications For Oligonucleotide Synthesis
Formula C42H53N6O7P
Molecular Weight 784.88
SMILES
O=C1NC(NC(C(C)C)=O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)[C@@H](OP(N(C(C)C)C(C)C)C)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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