Fig. 1 · Structure

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5'(E)-VP-2'-OMe-Bz-A Phosphoramidite

Nucleotide Precursor

5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a phosphoramidate nucleotide precursor utilized in the synthesis of stable and functionalized modified oligonucleotides. This compound plays a critical role in the development of nucleic acid-based therapeutics and enables precise manipulation of nucleic acid structures for various research applications. Its unique properties support advancements in genomic studies and drug development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2419895-65-9
Applications Nucleotide Precursor
Formula C40H57N7O12P2
Molecular Weight 889.87
SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OCCC#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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