5-Ethynyl-2'-deoxyuridine-13C is a stable isotope-labeled analogue of 5-Ethynyl-2'-deoxyuridine (EdU), targeting cellular DNA during replication. This compound is incorporated into DNA and allows for visualization through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) in Click chemistry applications. EdU-13C serves as a sensitive and efficient probe for assessing cell proliferation, making it invaluable for research in cell biology and drug development. Additionally, it can function as a linker in the synthesis of PROTACs, facilitating studies in targeted protein degradation.
5-Ethynyl-2'-deoxyuridine-13C is a stable isotope-labeled analogue of 5-Ethynyl-2'-deoxyuridine (EdU), targeting cellular DNA during replication. This compound is incorporated into DNA and allows for visualization through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) in Click chemistry applications. EdU-13C serves as a sensitive and efficient probe for assessing cell proliferation, making it invaluable for research in cell biology and drug development. Additionally, it can function as a linker in the synthesis of PROTACs, facilitating studies in targeted protein degradation.
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