Fig. 1 · Structure
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5-Fluoro-α-methyltryptamine hydrochloride
5-HT Activator
5-Fluoro-α-methyltryptamine hydrochloride is a potent 5-HT activator that enhances intracellular levels of serotonin (5-HT) and subsequently promotes its release. This compound demonstrates significant efficacy with EC50 values of 37 nM for dopamine (DA), 14 nM for serotonin (5-HT), 78 nM for norepinephrine (NE), and 8.47 nM for the 5-HT2A receptor. Its application in research includes studying serotonin-related pathways and neuropharmacological effects, making it valuable for investigations in behavioral science and psychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 776-56-7 |
| Applications | 5-HT Activator |
| Formula | C11H14ClFN2 |
| Molecular Weight | 228.69 |
| SMILES | FC1=CC2=C(NC=C2CC(C)N)C=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.