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5-Fluorouracil-13C4,15N2

Stable Isotope

5-Fluorouracil-13C4,15N2 is a stable isotope-labeled form of 5-Fluorouracil (5-FU), a uracil analog known for its potent antitumor properties. This compound primarily targets thymidylate synthetase, leading to the inhibition of pyrimidine synthesis and subsequent depletion of intracellular dTTP pools. As a result, 5-Fluorouracil-13C4,15N2 induces apoptosis in cancer cells and may serve as a chemical sensitizer in therapeutic applications. Additionally, it exhibits inhibitory effects against HIV, making it relevant for diverse biological research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	202407-03-2
Applications	Stable Isotope
Formula	13C4H3F15N2O2
Molecular Weight	136.03
Synonyms	5-FU-13C4,15N2
SMILES	O=[13C]1[13C](F)=[13CH][15NH][13C]([15NH]1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.