5-Fluorouracil-13C4,15N2 is a stable isotope-labeled form of 5-Fluorouracil (5-FU), a uracil analog known for its potent antitumor properties. This compound primarily targets thymidylate synthetase, leading to the inhibition of pyrimidine synthesis and subsequent depletion of intracellular dTTP pools. As a result, 5-Fluorouracil-13C4,15N2 induces apoptosis in cancer cells and may serve as a chemical sensitizer in therapeutic applications. Additionally, it exhibits inhibitory effects against HIV, making it relevant for diverse biological research.
5-Fluorouracil-13C4,15N2 is a stable isotope-labeled form of 5-Fluorouracil (5-FU), a uracil analog known for its potent antitumor properties. This compound primarily targets thymidylate synthetase, leading to the inhibition of pyrimidine synthesis and subsequent depletion of intracellular dTTP pools. As a result, 5-Fluorouracil-13C4,15N2 induces apoptosis in cancer cells and may serve as a chemical sensitizer in therapeutic applications. Additionally, it exhibits inhibitory effects against HIV, making it relevant for diverse biological research.
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