Fig. 1 · Structure
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5-Fluorouridine 5'-phosphate
ODCase Inhibitor
5-Fluorouridine 5'-phosphate is an inhibitor of orotidine-5'-monophosphate decarboxylase (ODCase), demonstrating a Ki value of 98 µM for human ODCase and 645 µM for Methanobacterium ODCase. This compound exhibits significant inhibitory activity against leukemia and lymphoma cell lines, making it a valuable tool in cancer research applications. 5-Fluorouridine 5'-phosphate is utilized to study metabolic pathways and therapeutic strategies in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 796-66-7 |
| Applications | ODCase Inhibitor |
| Formula | C9H12FN2O9P |
| Molecular Weight | 342.17 |
| SMILES | O=C(N1)N([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C=C(F)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.