Fig. 1 · Structure
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5-Formyl-2'-deoxyuridine
Nucleic Acid Derivative
5-Formyl-2'-deoxyuridine is an oxidized nucleic acid derivative that serves as a biomarker for oxidative DNA damage, resulting from the oxidation of the 5-methyl group of thymine. This compound is particularly useful in research focused on DNA damage and repair mechanisms. Furthermore, it can be utilized in studies involving chemical crosslinking with peptides from the RecA protein, facilitating investigations into the interactions between DNA repair proteins and nucleic acids.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4494-26-2 |
| Applications | Nucleic Acid Derivative |
| Formula | C10H12N2O6 |
| Molecular Weight | 256.21 |
| SMILES | OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C=O)C(NC2=O)=O)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.