5'-Guanidinonaltrindole hydrochloride is a potent and selective κ-opioid receptor antagonist, exhibiting a Ki of 0.18 nM for the human κ-opioid receptor. This compound is employed in research to explore the roles of κ-opioid receptors in pain modulation, mood disorders, and addiction pathways. Its high affinity makes it a valuable tool for studies investigating the pharmacological effects of κ-opioid receptor inhibition.
5'-Guanidinonaltrindole hydrochloride is a potent and selective κ-opioid receptor antagonist, exhibiting a Ki of 0.18 nM for the human κ-opioid receptor. This compound is employed in research to explore the roles of κ-opioid receptors in pain modulation, mood disorders, and addiction pathways. Its high affinity makes it a valuable tool for studies investigating the pharmacological effects of κ-opioid receptor inhibition.
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