Fig. 1 · Structure
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5'-Guanylic acid disodium salt
Nucleotide
5'-Guanylic acid disodium salt is a purine nucleotide that primarily functions as a signaling molecule in various physiological processes, including energy metabolism and gene expression regulation. It plays a crucial role in modulating genes associated with fatty acid metabolism. Additionally, this compound acts as a weak agonist for ionotropic glutamate receptors (iGluR), thereby reducing glutamatergic activity and exerting neuroprotective effects. However, at elevated concentrations, 5'-Guanylic acid disodium salt can induce neuronal cell death, making it valuable for studies on neuroprotection and excitotoxicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 5550-12-9 |
| Applications | Nucleotide |
| Formula | C10H12N5Na2O8P |
| Molecular Weight | 407.18 |
| Synonyms | 5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt |
| SMILES | O=P(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O[Na])O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.