5-HT2A/5-HT2C inverse agonist 1 functions as a potent dual inverse agonist at the 5-HT2A and 5-HT2C receptors, demonstrating minimal hERG channel inhibition to mitigate cardiovascular risks. This compound exhibits significant antipsychotic effects in the MK-801-induced mouse model, making it a valuable tool for the investigation of psychotic disorders. It is particularly relevant for studies aiming to elucidate the molecular mechanisms underlying psychosis and for the development of new therapeutic strategies.
5-HT2A/5-HT2C inverse agonist 1 functions as a potent dual inverse agonist at the 5-HT2A and 5-HT2C receptors, demonstrating minimal hERG channel inhibition to mitigate cardiovascular risks. This compound exhibits significant antipsychotic effects in the MK-801-induced mouse model, making it a valuable tool for the investigation of psychotic disorders. It is particularly relevant for studies aiming to elucidate the molecular mechanisms underlying psychosis and for the development of new therapeutic strategies.
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