5-HT2A antagonist 3

Catalog No.: A29883
5-HT2A Antagonist
5-HT2A Antagonist 3 is a selective antagonist and inverse agonist of the 5-HT2A receptor with a pIC50 of 8.7 and a pKi of 9. This compound exhibits significant biological activity relevant to neurological research, providing insights into 5-HT2A receptor-mediated pathways and their implications in various neuropsychiatric disorders. It serves as a valuable tool in the study of serotonin receptor interactions and the development of therapeutic agents targeting these pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5-HT2A Antagonist 3 is a selective antagonist and inverse agonist of the 5-HT2A receptor with a pIC50 of 8.7 and a pKi of 9. This compound exhibits significant biological activity relevant to neurological research, providing insights into 5-HT2A receptor-mediated pathways and their implications in various neuropsychiatric disorders. It serves as a valuable tool in the study of serotonin receptor interactions and the development of therapeutic agents targeting these pathways.
Product Information
Catalog NumA29883
FormulaC25H34FN3O3
Molecular Weight443.55
CAS Number1134815-69-2
SMILESO=C(N(C1CCN(CC1)C)CC2=CC=C(C=C2)F)NCC3=CC=C(C=C3)OCC(C)(C)O
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