Fig. 1 · Structure

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5-HT2A antagonist 3

5-HT2A Antagonist

5-HT2A Antagonist 3 is a selective antagonist and inverse agonist of the 5-HT2A receptor with a pIC50 of 8.7 and a pKi of 9. This compound exhibits significant biological activity relevant to neurological research, providing insights into 5-HT2A receptor-mediated pathways and their implications in various neuropsychiatric disorders. It serves as a valuable tool in the study of serotonin receptor interactions and the development of therapeutic agents targeting these pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1134815-69-2
Applications 5-HT2A Antagonist
Formula C25H34FN3O3
Molecular Weight 443.55
SMILES
O=C(N(C1CCN(CC1)C)CC2=CC=C(C=C2)F)NCC3=CC=C(C=C3)OCC(C)(C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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