Fig. 1 · Structure
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5-HT2B antagonist-1
5-HT2B Receptor Antagonist
5-HT2B antagonist-1 is an orally active antagonist of the 5-HT2B receptor, exhibiting an IC50 value of 33.4 nM. This compound is useful for investigating the role of 5-HT2B receptor signaling in various pathologies, including hepatocellular carcinoma, cardiovascular disorders, and gastrointestinal diseases. It provides a valuable tool for researchers studying the therapeutic potential of targeting 5-HT2B receptors in disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 393129-91-4 |
| Applications | 5-HT2B Receptor Antagonist |
| Formula | C11H14BrN5 |
| Molecular Weight | 296.17 |
| SMILES | BrC1=CC=C(NC2=NC(N)=NC(C)(C)N2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.