5-HT2CR Agonist 2 is a selective agonist targeting the 5-HT2C receptor, demonstrating an EC50 of 36 nM. This compound effectively penetrates the blood-brain barrier and exhibits Gq-biased signaling. It has been shown to attenuate MK801-induced hyperlocomotion and reverse hyperlocomotor activity induced by phencyclidine, making it a valuable tool for research into neuropsychiatric disorders and the modulation of dopaminergic activity.
5-HT2CR Agonist 2 is a selective agonist targeting the 5-HT2C receptor, demonstrating an EC50 of 36 nM. This compound effectively penetrates the blood-brain barrier and exhibits Gq-biased signaling. It has been shown to attenuate MK801-induced hyperlocomotion and reverse hyperlocomotor activity induced by phencyclidine, making it a valuable tool for research into neuropsychiatric disorders and the modulation of dopaminergic activity.
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