Fig. 1 · Structure
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5-HT6/5-HT2A receptor ligand-2
5-HT6/5-HT2A Receptor Antagonist
5-HT6/5-HT2A receptor ligand-2 is a potent dual antagonist of the 5-HT6 and 5-HT2A receptors, demonstrating Ki values of 25 nM and 32 nM, respectively. This compound exhibits pro-cognitive properties, making it a valuable tool for research in neuroscience and psychiatric disorders. Its ability to penetrate the blood-brain barrier enhances its potential applications in studying cognitive function and related therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2411088-16-7 |
| Applications | 5-HT6/5-HT2A Receptor Antagonist |
| Formula | C20H18FN3O2 |
| Molecular Weight | 351.37 |
| SMILES | OC1=CC=C(C2=CC=C(CNCCC3=CNC4=NC=C(F)C=C43)O2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.