5-HT6/5-HT2A receptor ligand-2

Catalog No.: A29897
5-HT6/5-HT2A Receptor Antagonist
5-HT6/5-HT2A receptor ligand-2 is a potent dual antagonist of the 5-HT6 and 5-HT2A receptors, demonstrating Ki values of 25 nM and 32 nM, respectively. This compound exhibits pro-cognitive properties, making it a valuable tool for research in neuroscience and psychiatric disorders. Its ability to penetrate the blood-brain barrier enhances its potential applications in studying cognitive function and related therapeutics.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5-HT6/5-HT2A receptor ligand-2 is a potent dual antagonist of the 5-HT6 and 5-HT2A receptors, demonstrating Ki values of 25 nM and 32 nM, respectively. This compound exhibits pro-cognitive properties, making it a valuable tool for research in neuroscience and psychiatric disorders. Its ability to penetrate the blood-brain barrier enhances its potential applications in studying cognitive function and related therapeutics.
Product Information
Catalog NumA29897
FormulaC20H18FN3O2
Molecular Weight351.37
CAS Number2411088-16-7
SMILESOC1=CC=C(C2=CC=C(CNCCC3=CNC4=NC=C(F)C=C43)O2)C=C1
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