5-HT6R antagonist 5

Catalog No.: A29903
5-HT6R Antagonist
5-HT6R antagonist 5 is a potent competitive antagonist of the 5-HT6 receptor, exhibiting an IC50 value of 4.19 nM. This compound is instrumental in the exploration of central nervous system disorders, as well as in studies related to cognitive and neurodegenerative diseases. Its ability to modulate 5-HT6R signaling makes it a valuable tool for investigating therapeutic strategies in these challenging conditions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description5-HT6R antagonist 5 is a potent competitive antagonist of the 5-HT6 receptor, exhibiting an IC50 value of 4.19 nM. This compound is instrumental in the exploration of central nervous system disorders, as well as in studies related to cognitive and neurodegenerative diseases. Its ability to modulate 5-HT6R signaling makes it a valuable tool for investigating therapeutic strategies in these challenging conditions.
Product Information
Catalog NumA29903
FormulaC19H24N6O2S
Molecular Weight400.50
CAS Number1220645-15-7
SMILESO=S(C1=CC=CC=C1)(C2=C(N=C(C)C=C3N4CCN(CC4)C)N3N=C2NC)=O
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