Fig. 1 · Structure
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5-HT7R antagonist 2
5-HT7R Antagonist
5-HT7R Antagonist 2 specifically targets the 5-HT7 receptor, functioning as a potent antagonist that inhibits G protein and β-arrestin signaling pathways, with a Ki value of 67 nM. This compound exhibits biological activities relevant to neurogenesis and has shown potential in reducing repetitive behaviors associated with autism spectrum disorder (ASD). It is an important tool for research applications focused on neurodevelopmental disorders and signaling pathway modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1448808-50-1 |
| Applications | 5-HT7R Antagonist |
| Formula | C16H16N2O |
| Molecular Weight | 252.31 |
| SMILES | COC1=C(C2=CC=CC(C3=NCCN3)=C2)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.