Fig. 1 · Structure
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5-Hydroxy-2'-deoxyuridine
Oxidation Product of 2'-Deoxycytidine
5-Hydroxy-2'-deoxyuridine (5-OHdU) is an oxidation product of 2'-Deoxycytidine, serving as a vital marker for oxidative stress in DNA. It can be incorporated into DNA strands in vitro via DNA polymerase, making it a useful tool for studying DNA replication, repair mechanisms, and the effects of oxidative damage. Its applications extend to cancer research, pharmacology, and studies of mutagenesis and aging-related processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5168-36-5 |
| Applications | Oxidation Product of 2'-Deoxycytidine |
| Formula | C9H12N2O6 |
| Molecular Weight | 244.20 |
| Synonyms | 5-OHdU |
| SMILES | O[C@H]1C[C@H](N2C(NC(C(O)=C2)=O)=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.