Fig. 1 · Structure
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5-Hydroxy indomethacin
Indomethacin Metabolite
5-Hydroxy indomethacin is a metabolite of Indomethacin, primarily characterized by its role in the biotransformation processes of nonsteroidal anti-inflammatory drugs (NSAIDs). This compound exhibits anti-inflammatory activity and is utilized in studies focused on pharmacokinetics and drug metabolism. Its relevance extends to investigating the therapeutic effects and safety profiles of NSAIDs in various biological assays.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2504-32-7 |
| Applications | Indomethacin Metabolite |
| Formula | C18H14ClNO4 |
| Molecular Weight | 343.76 |
| Synonyms | O-Desmethyl indomethacin |
| SMILES | CC1=C(C2=C(N1C(C3=CC=C(Cl)C=C3)=O)C=CC(O)=C2)CC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.