Fig. 1 · Structure
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5-Hydroxycytidine
Modified Nucleoside
5-Hydroxycytidine is a modified nucleoside that plays a crucial role in RNA biology, particularly in the 23S rRNA of Escherichia coli. It specifically targets the C2501 site, demonstrating increased modification levels in stationary phase cells. This compound has been associated with enhanced stability and functional resilience in radiation-resistant bacterial strains compared to traditional E. coli, making it valuable for studies in RNA modification and cellular responses to stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 39638-73-8 |
| Applications | Modified Nucleoside |
| Formula | C9H13N3O6 |
| Molecular Weight | 259.22 |
| SMILES | O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(C(O)=C2)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.