Fig. 1 · Structure
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5-Hydroxydecanoic acid
KATP Channel Antagonist
5-Hydroxydecanoic acid (5-HD) is a selective antagonist of KATP channels, capable of inhibiting channel activity during ischemic conditions by competing with ATP for the binding site. This agent specifically targets the KATP channels in cardiac tissues and spares those in pancreatic cells, making it a valuable tool for studying the physiological role of KATP channels in ischemia and related disorders. Its unique mechanism of action positions 5-HD as an important reagent in cardiovascular research aimed at understanding ischemic preconditioning and protective strategies against cardiac injury.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 624-00-0 |
| Applications | KATP Channel Antagonist |
| Formula | C10H20O3 |
| Molecular Weight | 188.26 |
| SMILES | O=C(CCCC(CCCCC)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.