Fig. 1 · Structure
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5-Hydroxymethyl-2’-deoxycytidine
Epigenetic Modification
5-Hydroxymethyl-2'-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine and plays a significant role in epigenetic modification within DNA. This compound is involved in cellular processes and can act as a marker for irreversibly damaged cells, making it valuable in research focused on cellular stress responses, DNA repair mechanisms, and epigenetic profiling. Its use in studies can facilitate a deeper understanding of various biological phenomena related to gene expression and cellular health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 7226-77-9 |
| Applications | Epigenetic Modification |
| Formula | C10H15N3O5 |
| Molecular Weight | 257.24 |
| Synonyms | 5hmdC |
| SMILES | O[C@H]1C[C@H](N2C(N=C(N)C(CO)=C2)=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.