Fig. 1 · Structure
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5-Methoxysterigmatocystin
Cytotoxin
5-Methoxysterigmatocystin is a mycotoxin that functions primarily as a cytotoxin. It has been demonstrated to exhibit significant cytotoxic activity against cancer cell lines, including A549 and HepG2, with IC50 values of 5.5 μM and 0.7 μM, respectively. Additionally, 5-Methoxysterigmatocystin is capable of inducing DNA damage and acts as a photosensitizer, generating singlet oxygen (1O2) upon exposure to visible light. This compound is valuable for research applications focusing on cancer biology and DNA damage mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 22897-08-1 |
| Applications | Cytotoxin |
| Formula | C19H14O7 |
| Molecular Weight | 354.31 |
| SMILES | O=C1C2=C(OC3=C1C(O)=CC=C3OC)C4=C(O[C@]5([H])[C@@]4([H])C=CO5)C=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.