Fig. 1 · Structure
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5-Methylcytosine-d4
Stable Isotope
5-Methylcytosine-d4 is a stable isotope-labeled form of 5-Methylcytosine, a significant DNA modification present in both prokaryotic and eukaryotic organisms. It plays a crucial role in the methylation of CpG dinucleotides, contributing to DNA stability and influencing RNA structure and mRNA translation. Additionally, it can be oxidized to form various forms of hydroxymethylated cytosines. This reagent is valuable for applications in epigenetics, developmental biology, and research into diseases such as colorectal cancer and hepatocellular carcinoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1219795-15-9 |
| Applications | Stable Isotope |
| Formula | C5H3D4N3O |
| Molecular Weight | 129.15 |
| SMILES | NC1=C(C([2H])=NC(N1)=O)C([2H])([2H])[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.