Fig. 1 · Structure
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5'-O-DMT-2'-O-TBDMS-Ac-rC
Modified Nucleoside
5'-O-DMT-2'-O-TBDMS-Ac-rC is a modified nucleoside designed for the synthesis of RNA and DNA oligomers. This compound features a 5'-O-dimethoxytrityl (DMT) protecting group, a 2'-O-tert-butyldimethylsilyl (TBDMS) modification, and an acetyl group, enhancing the stability and usability of nucleic acids during synthetic processes. It is particularly useful in molecular biology applications, including oligonucleotide synthesis and the study of RNA structures and functions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 121058-85-3 |
| Applications | Modified Nucleoside |
| Formula | C38H47N3O8Si |
| Molecular Weight | 701.88 |
| SMILES | O[C@@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N1C(N=C(NC(C)=O)C=C1)=O)O2)[C@H]2COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.