Fig. 1 · Structure

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5'-O-DMT-2'-O-TBDMS-rI

Modified Nucleoside

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside that serves as a valuable intermediate in nucleic acid synthesis. This compound facilitates the incorporation of ribonucleic acid (RNA) analogs, enabling researchers to explore various biochemical pathways and develop RNA-based therapeutics. Its unique structural modifications enhance the stability and utility of synthesized nucleic acids in various applications, including gene editing and molecular biology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 127212-34-4
Applications Modified Nucleoside
Formula C37H44N4O7Si
Molecular Weight 684.85
SMILES
O[C@@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N1C(N=CNC2=O)=C2N=C1)O3)[C@H]3COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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