Fig. 1 · Structure
Documents & Downloads
5'-O-DMT-2'-TBDMS-Uridine
Deoxyribonucleoside
5'-O-DMT-2'-TBDMS-Uridine is a modified deoxyribonucleoside that serves as a key building block in oligonucleotide synthesis. Its protective groups facilitate the coupling of nucleotides while enhancing stability during synthesis processes. This reagent is crucial for applications in molecular biology, including the development of antisense oligonucleotides and RNA interference studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 81246-80-2 |
| Applications | Deoxyribonucleoside |
| Formula | C36H44N2O8Si |
| Molecular Weight | 660.83 |
| SMILES | O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.