Fig. 1 · Structure
Documents & Downloads
5'-O-DMT-dT
Nucleoside Derivative
5'-O-DMT-dT, or 5'-O-(4,4'-Dimethoxytrityl)thymidine, is a nucleoside derivative primarily utilized in oligonucleotide synthesis. This reagent serves as a protective group for the 5' hydroxyl of thymidine, facilitating the assembly of DNA fragments with enhanced stability and compatibility. Its application is crucial in various molecular biology techniques, including primer design and functional nucleic acid research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 40615-39-2 |
| Applications | Nucleoside Derivative |
| Formula | C31H32N2O7 |
| Molecular Weight | 544.59 |
| Synonyms | 5'-O-(4,4'-Dimethoxytrityl)thymidine |
| SMILES | O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.