Fig. 1 · Structure
Documents & Downloads
5'-O-DMT-N4-Ac-2'-F-dC
Modified Nucleoside
5'-O-DMT-N4-Ac-2'-F-dC is a modified nucleoside that features a 2'-fluoro substitution and an acetylation on the N4 position. This nucleotide is primarily utilized in the synthesis of modified oligonucleotides, enabling enhanced stability and specificity in nucleic acid research. Its unique structural modifications make it valuable for applications in antisense therapies, RNA interference studies, and other nucleic acid-related research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 159414-98-9 |
| Applications | Modified Nucleoside |
| Formula | C32H32FN3O7 |
| Molecular Weight | 589.61 |
| SMILES | COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](O)[C@@H](F)[C@H](N5C(N=C(NC(C)=O)C=C5)=O)O4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.